Skipping doses or significantly delaying them allows medication levels to drop below therapeutic thresholds, potentially reducing effectiveness and triggering increased appetite or cravings
10.1126/scitranslmed.3010473 Summary Keywords osmolytes, chemical chaperones, TMAO, betaine, choline, cardiovascular disease, liver disease Citation Ilyas A, Wijayasinghe YS, Khan I, El Samaloty NM, Adnan M, Dar TA, Poddar NK, Singh LR, Sharma H and Khan S (2022) Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds
GLP-1 also activates receptors in the brain and stomach, helping to regulate appetite and digestion
See the testing with a third party as some kind of insurance coverage to confirm the product is indeed pure and dosed correctly