In educational frameworks that map peptides to the underlying driver of decline, DSIP falls into the neurocognitive and sleep category, alongside mechanistically distinct compounds such as Semax and Selank
Monti DA, Newberg AB, Forehand V, et al
GIP Agonism Reduces appetite, nausea, and bone resorption Increases insulin & glucagon production, and lipogenesis Glucagon Agonism Reduces appetite, food intake, and gastric emptying Increases insulin production, energy expenditure, and nausea Amylin Agonism Reduces appetite, food intake, glucagon production, and gastric emptying Increases energy expenditure Reduces bone resorption and increases bone production PYY Agonism Reduces appetite, food intake, and gastric emptying Increases energy expenditure and nausea The Cost Challenge for Payers The cost of GLP-1s continues to be a significant concern for payers between skyrocketing costs and utilization over the past several years
But also just really having change agents going all the way back down to sending people just little reminders in form of a gift or something