Phase II data showed up to 24.2% mean body weight reduction at 48 weeks at the highest dose approximately 10 percentage points above semaglutide's best observed outcome
2, May 2016, pp
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Dosing & Administration Guide Rybelsus Titration Schedule Rybelsus is taken once daily, starting with a low dose that is gradually increased based on blood sugar levels and HbA1c measurements: Step 1: Start with 3mg once daily for 30 days Step 2: Increase to 7mg once daily for at least 30 days Step 3: May increase to 14mg once daily if additional glycemic control is needed Critical administration requirements: Rybelsus must be taken on an empty stomach with no more than 4 ounces (120mL) of plain water
