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544 GLP-1 has pleiotropic actions due to the extensive expression of GLP-1 receptors (GLP-1R) in multiple organs, including microglia and astrocytes across various brain regions, thus is being explored for its potential in neurodegenerative diseases

Reducing sugary foods and refined carbohydrates may also help manage blood sugar levels

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Most of the peptides examined in the studies (especially in the papers where this mechanism is mentioned) contain specific sequences that allow them to cross the lipid membrane, such as the so-called cell-penetrating peptides (CPPs)