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[1] Licensed pharmacological options in the UK include orlistat (available at BMI 30 kg/m, or 28 kg/m with weight-related risk factors) and semaglutide (available within specialist weight management services as per NICE TA875, with adjusted BMI thresholds for some ethnic groups)

A parallel in vitro study indicated that Pycnogenol does this by inhibiting markers of inflammation

The significance of specific microbial shifts, such as an increased Firmicutes / Bacteroidetes ratio, extends beyond a mere descriptive biomarker

It is a dual agonist that targets both the GLP-1 (glucagon-like peptide-1) and GIP (gastric inhibitory polypeptide) receptors, helping to regulate blood sugar levels while also promoting weight loss