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Core Hormones in Female HRT Each plays a distinct role in your health and well-being

The primary research outcome was the severity of depressive disorder which was assessed using the second version of the Beck Depression Inventory-II (BDI-II), and a 50% reduction of the baseline BDI score was considered as the treatment response

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Biological analyses were performed on plasma samples, quantifying total and reduced glutathione, oxidized glutathione and redox ratios using HPLC with colorimetric detection, while behavioral outcomes were assessed weekly through standardized caregiver questionnaires and clinician-rated scales