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The mutation of the Clathrin box showed a significant reduction in FRET efficiency for Ent1-mNeonGreen when compared to wildtype Chc (8% for WT vs

PMID: 16962140 DOI: 10.1016/j.jns.2006.06.007 Keywords Soman (GD) Drug Class: Organophosphate Chemical Warfare Agent classified as a Nerve Agent Mechanism of Action: Inhibits the destruction of acetylcholine by cholinesterase Aging occurs within a half-life of only 2 minutes with soman Rapid aging can make it almost impossible to give pralidoxime rapidly enough to be beneficial after the first noticeable detection of symptoms of poisoning are felt, at which point a significant degree of aging has already occurred

The compounds documented research effects include modulation of an estimated 4,000+ genes, support for wound healing pathways, and signal effects in skin and hair follicle research models

Here, we review the metabolic role of the kidney in amino acid metabolism and describe how different diseases of the kidney lead to aberrations in amino acid metabolism