semaglutide aging A new study from UC San Diego offers early clinical evidence that semaglutide, a widely used GLP-1 receptor agonist, may slow biological aging. In a randomized, placebo-controlled trial, researchers observed a 9% 💉 Ozempic may be doing

These molecules are administered mainly by sub-cutaneous injection, and as such, remain in the peripheral bloodstream for a long period of time (with half-lives of days), but have little access to the intestinal vagal afferents

Brands like Ozempic and Wegovy have become household names, and a wide range of competitors are entering the market

Li Y, Chigurupati S, Holloway HW, Mughal M, Tweedie D, Bruestle DA, Mattson MP, Wang Y, Harvey BK, Ray B, et al

The parent compound, which is nontoxic, is extensively metabolized in the liver to form principally the sulfate and glucuronide conjugates which are also nontoxic and are rapidly excreted in the urine