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A C20 fatty diacid moiety, attached at position 17 via a gamma-glutamic acid and aminoethoxyethoxyacetic acid (AEEA) linker, extends the peptides half-life by promoting albumin binding, which slows clearance from the body

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But if something has a particularly prominent benefit, and theres a fairly easy strategy for side effects, for instance, tremor that can be treated with beta blockers or GI upset that could be treated with proton pump inhibitors

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