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Pendulum has not demonstrated anything close to those numbers

Notably, Nicolau et al 8 reported a significant PASI reduction from 10 to 5.1 and DLQI improvement from 12.7 to 6.4 in patients with obesity without diabetes treated with liraglutide

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reported an association between a common IGF-1 genetic haplotype, plasma IGF-1 levels and mammographic density in postmenopausal Norwegian women [36] while neither a single SNP, nor any diplotype (combination of two haplotypes) was associated with circulating IGF-1 levels in a multivariate analysis of Swedish women