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Among the patients, one patient developed rupture of esophageal varices after registration in this trial and was excluded from the current analysis

We have taken advantage of the ease with which ligand complexes can be produced in GR crystals, a property that extends to the isomorphous GRTR crystals, and have produced and analyzed crystals of GRTR complexes with glutathione, trypanothione, glutathionylspermidine and of a true catalytic intermediate, the mixed disulfide between trypanothione and the enzyme

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The Wald test was applied to evaluate the significance of log2 fold changes for each gene, and P value correction was performed using the Benjamini-Hochberg (BH) method in small intestinal datasets