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This is due to: Higher doses possible with injectable forms More consistent absorption Fewer requirements around food timing Clinical studies suggest people using injectable semaglutide may lose 1015% of their body weight over time with proper support

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Incretins are one of the main DPP4 substrates

By promoting insulin secretion and reducing glucagon, semaglutide helps stabilize blood sugar levels, which can prevent spikes and crashes that often lead to increased hunger and overeating