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Exceeding this dose can lead to serious problems due to a metabolite of the drug being toxic to the liver
The demonstration that OEA is the most active endogenous ligand for GPR119 is of particular interest since previous work has demonstrated that OEA, when administered to laboratory animals, causes a significant reduction in food intake and body weight gain
View at PubMed Note on nomenclature: Reduced glutathione (GSH) is the biologically active thiol form, distinguished from oxidized glutathione (GSSG)
These results approach the efficacy of Roux-en-Y gastric bypass surgery, which typically produces 25-30% weight loss at one year
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