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Despite T1D children harbouring greater levels of pro-inflammatory mediators, including interferons and interleukins, in their intestine it has been proposed that such immune profiles are a consequence of disease progression rather than the cause of T1D or its exacerbation (Savilahti et al

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Whether rapid clearance translates into clinical benefit remains to be seen, but with Phase III trials underway and prevention studies testing pre-symptomatic intervention, Roche is betting big