The Lancet 392(10157):1519-1529 Gerstein HC, Sattar N, Rosenstock J, Ramasundarahettige C, Pratley R, Lopes RD, Lam CSP, Khurmi NS, Heenan L, Del Prato S, Dyal L, Branch K
the events leading to dysfunction of the methionine cycle due to lack of glutathione as well as direct effects on methionine synthase conspire to create a state of being that is contrary to good health
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His research highlights three key tissues as fundamental components in mammalian aging and longevity regulation: the hypothalamus (serving as the central control hub), skeletal muscle (functioning as an effector), and adipose tissue (acting as a modulator)
