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However, current evidence points to at least partial mediation through central mechanisms as direct activation of central GIPRs can suppress food intake and decrease body weight, whereas deletion of these receptors blunts such effects and protects against obesity by altering feeding behavior (NamKoong et al., 2017

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Neuroscience 137:80719, PMID: 16330153 Abramov AY, Canevari L, Duchen MR (2003) Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity

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Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer

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A couple of peptides actually lean the other way

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