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At the same time, metabolic reprogramming in neighboring cells during proliferation and differentiation processes also impacts tumor immunity

A post-hoc subgroup analysis of that trial suggested benefit of prasinezumab in subjects with faster progression [209] and a comparison of MDS-UPDRS progression during the 4-year open-label extension phase with historical controls showed divergent trajectories in favour of prasinezumab from year 2 of treatment onwards [210]

Prevention is key: Always use sterile needles, alcohol swabs, and single-use vials when possible

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