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When I ask Decotiis if theres maybe a mourning phase over the decreased interest in some peoples favorite pastimes dining out and drinking with friends, for example she says, Yeah, a little bit. However, she quickly adds: But when people see that theyre down two pants sizes So shes basically positing an unsettling paradox: Yes, it might cause depression, but obviously you wont be depressed if youre skinny! Still, Decotiis generally sees semaglutide having an effect on her patients thats the opposite of those Redditors experiences