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However, AOD 9604 therapy is not recommended for: Pregnant or breastfeeding individuals People with cancer history (because of the need for safety clearance due to the growth aspect) Individuals with uncontrolled chronic disease unless cleared by physician Always speak to your licensed healthcare provider before proceeding with peptide therapy to determine if its a fit for your health status and goals

Mechanistically, HSP70 diminishes the transcription of proinflammatory cytokines by directly binding to inhibit the Ser 536 phosphorylation and nuclear translocation of the NF -B p65 subunit [70]

Figure 1 Generally, hydrogen peroxide is produced in the cell to fight off bacteria or viruses

doi: 10.1056/NEJMOA1603827 37 LeRNguyenMTAllahwalaMAPsaltisJPMaratheCSMaratheJAet al