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These pseudo leukotrienes mimic the structure and function of cysteinyl leukotrienes (CysLTs), inflammatory molecules long associated with airway constriction and mucus production in asthma

Peroxisomal homeostasis in metabolic diseases and its implication in ferroptosis

Also, VacA impairs GSH metabolism in gastric epithelial cells weakening their resistance against oxidative stress or cellular redox regulation by GSH [59]

Indeed, in the realm of cancer therapy, targeting the FSP1-mediated anti-ferroptosis effect and promoting its pro-necroptosis or pro-apoptosis activity could enhance the sensitivity of tumor cells to radiotherapy and chemotherapy, thus providing a promising approach to overcoming drug and radiotherapy resistance