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Elevated levels of NNMT activity is associated with reduced cellular energy expenditure and increased fat storage

The blanket point holds: these compounds are sold for laboratory research only, none is an approved drug, and none has an established human dose

From Rat Studies to Human Extrapolation From rat studies, the remarkably consistent effective dose range of 0.0045 mg/lb to 0.0000045 mg/lb intraperitoneally (a 1000-fold range showing similar efficacy) worked across depression, anxiety, Parkinsons, stroke, schizophrenia, and seizure models

If youre experiencing persistent fatigue, weakness, or other symptoms, its important to consult with a healthcare provider to rule out any underlying nutrient deficiencies