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Together, these results support the possibility that peripheral immune-metabolic alterations are linked to neurodevelopmental pathways implicated in ASD, consistent with emerging evidence that immune signaling can influence brain development

Concurrently, moderate levels of ROS serve as critical secondary messengers that activate key pro-survival and proliferative signaling pathways including MAPK, PI3K/AKT, NF-B, and HIF-1

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The fragile structure of glutathione makes surviving the digestive tract nearly impossible