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Blood was collected from the tail vein and blood glucose levels was measured before the injection and 4, 8, 10, 24 and 48 h after dosing in fed conditions

Additional mechanistic insights have further delineated the complexity of mitophagy regulation in EMS

In the current study, we first show in a large multicenter cohort of primary malignant peripheral nerve sheath tumors and second in a series of primary and metastatic melanomas that complete loss of H3K27 trimethylation is not a reliable marker to distinguish malignant peripheral nerve sheath tumor from melanoma

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