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Lancet 394(10192):3950
A 2024 study published in Nature Scientific Reports surveying over 162,000 patients over an eight-year period reported a significant association of psychiatric symptoms in patients taking GLP-1 RAs, including a 195% risk of depression, 108% risk of anxiety, and 106% increased risk for suicidal behavior
Between 2024 and 2025, 13 major deals valued at $13.6 billion focused on multi-target regimens combining GLP-1s with agents such as amylin, myostatin, or calcitonin analogs
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