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Description

Augmented EMP flux in tumors induces concomitant upregulation of PFK1 expression, demonstrating a positive correlation with pathway metabolic efficiency [51]

Knig D et al

At week 72, for the efficacy estimand, tirzepatide MTD had greater reductions in percentage weight versus semaglutide MTD (mean [95% confidence interval (CI)] 6.2% [ 7.8, 4.6]) and waist circumference ( 5.4% [ 7.1, 3.7])