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Cellular superoxide dismutase (SOD) activity was assessed by quantifying the inhibition of superoxide-dependent adrenaline autooxidation in a spectrophotometer at 480 nm, as previously described [12]

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Kumar and Bachhawat hypothesized that this leads to the combination of cytosolic cysteine and glutathione depletion, which activates the ATP-depleting futile 5-oxoproline cycle

Several factors may contribute, including dietary choices, certain medical conditions, and even age