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JC-1 staining indicated reduced mitochondrial membrane stability, confirming mitochondrial dysfunction (Fig

Aging is associated with decreased reduced glutathione in cells and increased oxidized glutathione, indicating a pro-oxidizing shift in redox balance

In clinical trials, people taking glutathione showed improved skin elasticity and fewer wrinkles compared to placebo

The present review discusses applications of epigenetic alterations affecting GSTP1 in cancer medicine used alone or in combination with other biomarkers for cancer detection and diagnosis as well as for future targeted preventive and therapeutic interventions including by dietary agents