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doi: 10.1016/bs.apcsb.2018.11.007 202 HatzirodosNIrving-RodgersHFHummitzschKHarlandMLMorrisSERodgersRJ

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Microdoses of 0.25 or 0.5 mg per week are effective for some and have low side effects

Community-reported seasonal protocols commonly cycle (8 weeks on, 8 weeks off, per the melanotan-1 dosing guide), sometimes citing receptor desensitization as the rationale