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Chronic exposure to pollutants, heavy metals, and endocrine-disrupting chemicals, as well as lifestyle habits such as smoking, an ultra-processed diet, and chronic stress, leads to redox imbalance in both oocytes and the ovarian microenvironment

Squamous cell cancer of the esophagus, mouth, and pharynx, which is more frequent among heavy smokers and heavy drinkers, was linked in case-controlled study to vitamin D deficiency

However, it is not currently FDA-approved for any condition and is expected to remain in the investigational phase for the near future

[4] [3] At the time of writing, NICE guidance for tirzepatide (Zepbound) in weight management is still evolving