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Patients who lose weight gradually while monitoring muscle mass and body fat percentage typically experience less facial deterioration

Al-Ayed M, Alshaybari K, Alshehri D, Jamaan A, Nasser I, Alaamri H, Alaseeri W, Mahfouz AA, Ali Alsareli S, Asaad AM, Ali Magzoub A, Qureshi MA, Shalayel MH

In addition, obesity causes metabolic tensions within the cell, leading to stress in the endoplasmic reticulum and overproduction of reactive oxygen species, causing damage to mitochondrial components and mitochondrial loss, and contributing to insulin resistance and causing greater activation of inflammatory cells [42]

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