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However, an in vitro study reported that supplementation with DHEA increases the mRNA and protein expression of the decidualization markers IGFBP1 and PRL, and may augment endometrial function and improve pregnancy rates (62)

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Given that the Purple Book lists so little patent information about brand biologic drugs, a prospective biosimilar maker cannot readily assess its risk of patent infringement litigation, and so must make investment and manufacturing decisions blindly