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In STEP 1, the largest trial (N = 1961), 38 participants were randomized to receive onceweekly subcutaneous semaglutide 2.4 mg or matching placebo for 68 weeks

Along with the direct activation of matrix metalloproteinase-2 (Bescond et al, 1999), vascular damage might also result from an impairment of the tertiary structure of connective tissue protein, because of the reduced degree of cross-linkage between collagen and fibrin monomers (Lubec et al, 1996a

Efficacy of rituximab in primary immune thrombocytopenia: an analysis of adult pretreated patients from everyday hematological practice

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