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DIO mice received 1, 5, 10 or 25 g per l per mouse of mGIPR-Ab/P3 or 25 g per l per mouse of IgG1 control injected ICV every 4 days for five treatments, with body weight and food intake monitored for 44 days

Here the Intrinsic Factor binds to the B12 and the "B12/IF Complex" enters the cells on the wall of the Ileum after binding to receptors on the surface of the Ileal cells, allowing it to enter the blood stream

The first injection is administered at Perfect B so the patient can learn the technique under clinical guidance