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6.1 Mechanisms underlying treatment of UC The treatment of UC involves the modulation of various immunoinflammatory pathways, including the activation and suppression of key mechanisms such as PPAR, Nrf2, NF-kB, and macrophages, along with the regulation of the Th17/Treg balance [61]

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Patients should not discontinue CPAP therapy without medical supervision and repeat sleep study confirmation of obstructive sleep apnea improvement