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They modulate neuronal excitability and synaptic function, which can exacerbate seizure activity and contribute to the chronic nature of the disease

Nevertheless, caution is warranted in individuals with diabetes or those at risk of hypoglycaemia, particularly if they are also taking insulin or a sulfonylurea

doi:10.1016/j.nurt.2010.05.014 Mogi M, Harada M, Riederer P, Narabayashi H, Fujita K, Nagatsu T (1994) Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients