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Though allergies to cobalt are rarely dangerous, taking any form of B12 supplement, whether by injection, tablet, or topically applied gel, may result in an uncomfortable, itchy rash

Starting at a microdose lets the body gently adjust to the medication, often eliminating the need for aggressive symptom management

Compared to individuals with obesity of other etiologies matched for BMI (body mass index), they have lower levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides

This increased gastric distension can promote the reflux of stomach contents back into the oesophagus, particularly when lying down or bending over