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Description

These data suggest that GSH synthesis, potentially through NRF2 repression, also limits NRF1 protein expression in the liver

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Cutaneous toxicities associated with vemurafenib therapy in 107 patients with BRAF V600E mutation-positive metastatic melanoma, including recognition and management of rare presentations

Extracellular signal-related kinases 1 and 2, an MAPK, and NFB specifically upregulate the expression of several IAP family members that attenuate apoptosis (137, 343)