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In laboratory settings, ipamorelin peptide is studied for its role in ghrelin receptor pathway interaction, receptor binding behavior, and intracellular signaling cascades under controlled experimental conditions

Cellular senescence in ovarian somatic cells, including GCs and stromal cells, may further exacerbate oxidative stress and inflammatory signaling within the follicular niche [80, 81, 82] Together, these interconnected mechanisms and hallmarks of aging suggest that reproductive aging shares common biological pathways with systemic aging, supporting the view that oocyte aging should be considered within a broader geroscience context