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Independent researchers typically administer a daily 5-amino-1MQ dose of 50-150mg of 5-amino-1MQ to human subjects

Tesamorelin's Phase 3 trials and Sermorelin's original approval studies were built around HIV-associated lipodystrophy and pediatric growth failure, not muscle building, so their bodybuilding use rests on extrapolation rather than direct testing

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Notes that high-dose niacin passes into breast milk and that lipid-altering doses could pose risks to nursing infants, recommending caution or avoidance of such doses during breastfeeding)