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Data Animal Data In a combined fertility and embryofetal development study in rats, subcutaneous doses of 0.01, 0.03 and 0.09 mg/kg/day (0.06-, 0.2-, and 0.6-fold the MRHD) were administered to males for 4 weeks prior to and throughout mating and to females for 2 weeks prior to mating, and throughout organogenesis to Gestation Day 17

Third case of a distinct variant of the EhlersDanlos syndrome (EDS)

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In the case of AHK, the copper atom is linked between the alanine and histidine residues of the alanine-histidine-lysine peptide