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The oxidative branch of the pentose phosphate pathway (PPP), driven primarily by the enzymes glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD), continues to serve as the dominant metabolic source of NADPH in most cells [42]

Additionally, the protein levels of SLC7A11 and SLC3A2 were found to be positively correlated with ER protein levels in ER+ breast cancer cell lines (Fig

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