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J Neuroinflammation 5:112 Sun L et al (2012) Combined administration of anisodamine and neostigmine produces anti-shock effects: involvement of 7 nicotinic acetylcholine receptors

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154 However, HIF-1 in islets is decreased in T2D, by hyperglycemia through inhibiting the HIF-1-HIF-1 dimer formation, and by NEFAs through increasing the proteolysis, leading to inability to initiate hypoxic adaptive responses