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These findings support the hypothesis that dampening of the GH pathway is the key contributor to lifespan extension in mice

Environmental factors such as stress, diet, toxins, and social interactions have been shown to induce epigenetic changes, including alterations in DNA methylation patterns

Because patients who discontinued WEGOVY during titration and those who did not reach the 2.4 mg weekly dose were not eligible for the randomized treatment period, the results may not reflect the experience of patients in the general population who are first starting WEGOVY

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