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Specifically, a meta-analysis of the ELIXA, LEADER, SUSTAIN-6, EXSCEL, REWIND and AMPLITUDE-O trials in type 2 diabetes estimated a 21% reduction in the risk of new-onset macroalbuminuria, eGFR decline, progression to ESKD or death attributable to kidney causes with GLP1-RAs compared with placebo [48]

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When prescribed in an internal medicine setting, this medication serves a dual purpose: treating obesity while simultaneously correcting metabolic dysfunction, thereby offering a comprehensive approach to preventing future chronic disease

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