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Has it invaded nearby tissues
The cardiovascular outcomes trial SUSTAIN-6, published in the New England Journal of Medicine, demonstrated cardiovascular safety in a population where many participants were receiving antiplatelet therapy
The working theory is that GLP-1s protect the heart through a combination of better metabolic control, lower inflammation, and direct vascular and cardiac benefits
For instance, research has shown that semaglutide can reduce inflammation, which is a significant factor in many chronic pain conditions
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