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The FDA requires extensive safety monitoring for all weight loss medications, and manufacturers must report adverse events, including cancer diagnoses

Given that previous studies have implicated transcriptional CDKs (e.g., CDK7, CDK9, CDK12/13) in SF3B1 phosphorylation 75,76,77,78,79 , we compared the effects of their inhibition with OTS964

Studies examining long-term human use of this peptide dont currently exist, leaving questions about extended-use safety unanswered