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Combining low-cost behavioral interventions with periodic GLP-1 therapy (rather than continuous use) may maximize cost-effectiveness

In the STEP 3 trial, 611 participants were randomly assigned to receive either semaglutide 2.4 mg or placebo in addition to intensive behavioral therapy to support a healthier lifestyle (3)

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Possible monitoring points include injection site reactions, swelling, joint discomfort, muscle aches, numbness or tingling, blood sugar changes, or fluid retention