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At the 12 mg dose, clinical trial data showed nausea in 28% of participants, diarrhea in 23%, constipation in 17%, and vomiting in 12%

Krupa et al., 2019)

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Psychological aspects of pain were examined with the Pain Beliefs and Perceptions questionnaire 99 , Beliefs in Pain Control Questionnaire (BPCQ) 100 , Pain Catastrophizing Scale 101 , and Your Experiences with Pain (Chronic Pain Stressor Scale, CPSS) 102