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It belongs to a class of drugs known as GLP-1 receptor agonists, which work by mimicking a natural hormone in the body called glucagon-like peptide-1 (GLP-1)

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More rarely, people can get more serious complications, like low blood sugar, pancreatitis or severe allergic reactions

SURMOUNT-5, published in the New England Journal of Medicine in 2025, directly compared tirzepatide to semaglutide