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How They Work: Zepbound is a dual agonist, meaning it activates both the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors

Reducose Mulberry Leaf Extract (250 mg per capsule) Reducose is a premium mulberry leaf extract standardized to 5% 1-Deoxynojirimycin (DNJ), delivering 12.5 mg DNJ per doseup to 50 more DNJ than typical mulberry extracts

Interestingly, even heterozygous Bbs5 +/ mice, which displayed normal body composition and energy metabolism compared with WT controls (Supplemental Figure 1, KV), were resistant to leptin (Supplemental Figure 3, K, L, O, and P), suggesting that leptin resistance may serve as a potential biomarker even in individuals with a single Bbs gene mutation

A drug that demonstrates 20% superiority in a global Phase 3 trial against resistant infections has transformative commercial potential